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24.11.25 - 13:24
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Wdh: Abnehmmittel als Alzheimer-Hoffnung: Novo Nordisk enttäuscht mit Studie (Cash)
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- Das Abnehmmittel Semaglutid des Pharmakonzerns Novo Nordisk hat in einer Alzheimer-Studie nicht den erwünschten Erfolg gebracht. Die zulassungsrelevante Phase-III-Studie Evoke zu Semaglutid in oraler Darreichungsform habe im Vergleich zu Placebo keine statistisch signifikante Verlangsamung des Fortschreitens der Alzheimer-Krankheit gezeigt, teilte der dänische Pharmariese am Montag mit. Der Aktienkurs von Novo Nordisk brach auf die Nachricht hin um zehn Prozent auf den tiefsten Stand seit dem Jahr 2021 ein./mis/stw...
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24.11.25 - 13:09
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Novo Nordisk scheitert bei Alzheimer – Aktie rauscht nach unten (Der Aktionaer)
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Die Aktie von Novo Nordisk rauscht zum Wochenstart ordentlich nach unten. Der Grund: Die Studien zu Rybelsus, basierend auf dem Wirkstoff Semaglutid, zum Einsatz bei Alzheimer zeigten nicht den erhofften Erfolg. In den Studien Evoke und Evoke+ konnte keine Verlangsamung des Krankheitsfortschritts erzielt werden....
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24.11.25 - 12:54
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Novo Nordisk enttäuscht mit Alzheimer-Studie (Cash)
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- Das Abnehmmittel Wegovy des Pharmakonzerns Novo Nordisk hat in einer Alzheimer-Studie nicht den erwünschten Erfolg gebracht. Die zulassungsrelevante Phase-III-Studie Evoke habe im Vergleich zu Placebo keine statistisch signifikante Verlangsamung des Fortschreitens der Alzheimer-Krankheit gezeigt, teilte der dänische Pharmariese am Montag mit. Der Aktienkurs von Novo Nordisk brach auf die Nachricht hin um zehn Prozent auf den tiefsten Stand seit dem Jahr 2021 ein./mis/stw...
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24.11.25 - 12:24
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Novo Nordisk A/S: Evoke phase 3 trials did not demonstrate a statistically significant reduction in Alzheimer′s disease progression (GlobeNewswire EN)
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Bagsværd, Denmark, 24 November 2025 – Novo Nordisk today announced the top-line results from the 2-year primary analysis of evoke and evoke+ phase 3 trials in early-stage symptomatic Alzheimer's disease. The two trials were randomised, double-blinded, enrolled a total of 3808 adults and evaluated the efficacy and safety of oral semaglutide compared to placebo on top of standard of care. The decision to pursue an Alzheimer's disease indication with semaglutide was based on real-world evidence studies, pre-clinical models as well as post-hoc analyses from diabetes and obesity trials....
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03.11.25 - 15:12
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MAI Capital Management Announces Expanded Office of Managing Partners Appointments Following Strategic Acquisition of Evoke Advisors (Business Wire)
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Partnership creates national RIA with 600 employees and $65 billion in AUMCLEVELAND--(BUSINESS WIRE)--MAI Capital Management (“MAI”), a registered investment advisor (RIA) focused on empowering clients to simplify, protect and grow their wealth, today announced it has completed its strategic partnership with Los Angeles-based RIA Evoke Advisors (“Evoke”). As part of this acquisition, MAI is introducing new Managing Partner appointments to help guide the firm's next chapter of growth and innovation.
With the completion of the acquisition, MAI scales to over $65 billion in assets under management (AUM) across 34 offices nationwide. This marks a landmark year for the firm, during which it has added over $30 billion in AUM and expanded its services for ultra-high-net-worth (UHNW) individuals, families and institutions. Integrating talent from both MAI and Evoke, the newly expanded Managing Partner team embodies MAI's dedication to delivering exceptional service and deep expertise for its full roster...
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20.10.25 - 14:36
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It′s still killing people, and the government has yet to act: Britain′s hidden asbestos epidemic | Tom White (The Guardian)
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Asbestos was banned in 1999, but as materials left in our buildings deteriorate, thousands of lives are being lost every yearHelen Bone was diagnosed with an asbestos-related cancer in 2021. She was 38. The type of cancer, mesothelioma, is incurable; the best prognosis is a few years, though most people don't get that long. “You always think of asbestos as a disease from decades ago – affecting men who worked in heavy industry – so to be diagnosed in my 30s is shocking,” she told the Northern Echo in 2022. “I want to see my children grow up but now I have to come to terms with the thought that this might not happen.” Sadly, Bone passed away in November last year, just three years after her diagnosis.For most people, the word “asbestos” will evoke previous eras: dusty Victorian and Edwardian factories; the shipyards of the interwar period; postwar building sites. Yet asbestos was not banned in the UK until 1999. According to the Health and Safety Executive (HSE), it still kills around 5,00...
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17.10.25 - 07:30
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Spa vibes with a grow-your-own-dinner option: Britain′s best new building is a revamped almshouse (The Guardian)
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With its shimmering ginkgo trees, tinkling pools and a rooftop garden, the Appleby Blue Almshouse housing complex for older people is a worthy winner of RIBA's prestigious Stirling prizeDescribed as “a provision of pure delight”, Appleby Blue Almshouse, a social housing complex for older people has been named this year's winner of the RIBA Stirling prize. With a vibe that has more in common with an Alpine spa hotel than the poky rooms and grim corridors usually associated with housing for elderly people, the building – by architects Witherford Watson Mann – reinvents the almshouse for the modern era as a place of care, shelter and social connection.As a building type, the origins of almshouses extend back centuries, giving a semblance of dignity to the poor, the old, the sick and the marginalised. Sequestered from the outside world, with cellular dwellings arrayed around courtyards, they evoke a sense of pastoral benevolence. Continue reading......
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12.10.25 - 18:18
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William Hill owner says it could shut up to 200 shops if Reeves raises gambling taxes (The Guardian)
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Evoke considering the plans before expected tax increases in budget, with up to 1,500 jobs potentially affectedThe debt-laden company behind William Hill is considering closing up to 200 betting shops if Rachel Reeves's autumn budget raises taxes on the gambling sector.Evoke, formerly known as 888, which acquired William Hill in a £2bn takeover in 2022, is drawing up plans for different scenarios before expected gambling tax increases in the chancellor's budget on 26 November. Continue reading......
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08.10.25 - 15:09
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MAI Capital Management Doubles Down on Organic Growth; Announces New Chief Marketing Officer (Business Wire)
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Former Focus Financial Partners executive to lead end-to-end client experience marketing strategy and advisor enablement initiativesCLEVELAND--(BUSINESS WIRE)--MAI Capital Management (“MAI”), a registered investment advisor (RIA) focused on empowering clients to simplify, protect and grow their wealth, today announced the hiring of Kathleen Alcorn as Chief Marketing Officer (“CMO”). Alcorn's appointment signals the latest step in MAI's strategy to elevate the firm into an industry-leading RIA, building on the momentum of its acquisition of Los Angeles-based Evoke Advisors. By investing in firms and talent that strengthen its national presence, MAI is enhancing both the client and advisor experience, while positioning the company for sustained growth.
Alcorn brings more than two decades of financial services marketing experience to MAI's leadership team. She has served as CMO at Focus Financial Partners and Nasdaq Corporate Solutions, where she was instrumental in building global brands and lead...
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