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Basel, March 29, 2026 – Novartis today announced final two-year results from the Phase III APPLAUSE‑IgAN study of Fabhalta® (iptacopan) in IgA nephropathy (IgAN). Fabhalta demonstrated a statistically significant, clinically meaningful improvement in estimated glomerular filtration rate (eGFR) slope, a key marker of kidney function, compared with placebo1. Fabhalta consistently outperformed placebo across key kidney outcomes over two years, demonstrating a slowing of disease progression and the potential to preserve kidney function in IgAN1.The results were published in the New England Journal of Medicine and simultaneously presented as late‑breaking data at the 2026 World Congress of Nephrology (WCN)....

CAMBRIDGE, Mass., March 28, 2026 (GLOBE NEWSWIRE) -- Biogen Inc. (Nasdaq: BIIB) announced positive results from the Phase 2 part of the AMETHYST Phase 2/3 study (Part A) of litifilimab in people living with cutaneous lupus erythematosus (CLE). Litifilimab is the first humanized IgG1 monoclonal antibody (mAb) targeting blood dendritic cell antigen 2 (BDCA2), which has the potential to become the first innovative therapy approved for CLE in 70 years. Part A of AMETHYST evaluated the efficacy and safety of litifilimab through week 24, with reductions in skin disease activity reported across several measures. Results are consistent with the earlier positive Phase 2 LILAC study reported in The New England Journal of Medicine. Phase 2 results from LILAC and AMETHYST supported litifilimab's recently granted U.S. Food and Drug Administration (FDA) Breakthrough Therapy Designation. Results are being presented today at the American Academy of Dermatology (AAD) Annual Meeting....

ZUG, Switzerland, March 28, 2026 – MoonLake Immunotherapeutics (NASDAQ: MLTX) (MoonLake or the Company), a clinical-stage biotechnology company focused on creating next-level therapies for inflammatory diseases, today announces long-term Week 40 results of the Phase 3 VELA-1 and VELA-2 clinical trials of its registrational global program in patients with moderate-to-severe HS and confirms the presentation of the data at the 2026 American Academy of Dermatology (AAD) Annual Meeting later today....

DURHAM, N.C., March 28, 2026 (GLOBE NEWSWIRE) -- Priovant Therapeutics, a clinical-stage biotechnology company focused on developing targeted therapeutics in autoimmune disease, announced today the publication of results from the Phase 3 VALOR trial evaluating brepocitinib in adults with dermatomyositis (DM) in the New England Journal of Medicine (NEJM)....

Decision of the US District Court for the Southern District of New York in the TriZetto re-trial...

Envudeucitinib late-breaking data at AAD: early and robust improvements in skin clearance, quality of life and psoriasis symptoms in two Phase 3 trials...

TORONTO, March 28, 2026 (GLOBE NEWSWIRE) -- (TSX: SPFD) Mulvihill Enhanced Split Preferred Share ETF (the “Fund”) (formerly Mulvihill U.S. Health Care Enhanced Yield ETF) announces results of operations for the year ended December 31, 2025. Increase in net assets attributable to holders of units amounted to $0.67 million or $0.31 per unit. As at December 31, 2025, net assets attributable to holders of units were $25.29 million or $9.36 per unit. Cash distributions to unitholders totaling $2.26 million or $1.00 per unit were paid during the year....

TORONTO, March 28, 2026 (GLOBE NEWSWIRE) -- (TSX: PGIC; PGIC.PR.A)  (the “Fund”) announces results of operations for the year ended December 31, 2025. Increase in net assets attributable to holders of Class A shares amounted to $3.62 million or $1.32 per Class A share.   As at December 31, 2025, net assets attributable to holders of Class A shares were $25.69 million or $6.77 per Class A share. Cash distributions of $0.75 per Preferred share and $0.96 per Class A share were paid during the year....

TORONTO, March 28, 2026 (GLOBE NEWSWIRE) -- (TSX: MPY) Mulvihill Premium Yield Fund (the “Fund”) announces results of operations for the year ended December 31, 2025. Increase in net assets attributable to holders of Class I units amounted to $1.29 million or $1.10 per Class I unit, increase in net assets attributable to holders of Class F units amounted to $1.25 million or $1.13 per Class F unit,   increase in net assets attributable to holders of Class A units amounted to $0.40 million or $0.46 per Class A unit, and increase in net assets attributable to holders of ETF units amounted to $0.84 million or $0.55 per ETF unit. As at December 31, 2025, net assets attributable to holders of Class I were $12.67 million or $10.93 per Class I unit; net assets attributable to holders of Class F were $12.62 million or $10.94 per Class F unit, net assets attributable to holders of Class A units were $7.21 million or $10.08 per Class A unit, and net asset attributable to holders of ETF units were $15.32 mill...

TORONTO, March 28, 2026 (GLOBE NEWSWIRE) -- (TSX: CBNK) Mulvihill Canadian Bank Enhanced Yield ETF (the “Fund”) announces results of operations for the year ended December 31, 2025. Increase in net assets attributable to holders of units amounted to $47.04 million or $3.75 per unit. As at December 31, 2025, net assets attributable to holders of units were $130.48 million or $11.86 per unit. Cash distributions to unitholders totaling $8.67 million or $0.70 per unit were paid during the year....

Arcutis Presents New Phase 2 Results in Infants with Atopic Dermatitis in Late-Breaking Session Today at 2026 AAD...

Featured presentation highlights positive BroADen Phase 1b atopic dermatitis trial results supporting KT-621's compelling oral profile...

AAD: new results from Sanofi's amlitelimab phase 3 studies in atopic dermatitis presented in late-breaking research session...

Rocket Lab successfully launched a pair of satellites for the European Space Agency (ESA) to test new navigation systems in low Earth orbit....

New data analyses from the Company's varoglutamstat Phase 2 program were presented at the World Congress of Nephrology....

(All dollar amounts are expressed in Canadian dollars, unless stated otherwise)...

Miata Metals Announces Grant of Stock Options...

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TORONTO, March 27, 2026 (GLOBE NEWSWIRE) -- Constellation Software Inc. (TSX:CSU) (“Constellation”) announced today that Mark Leonard, the founder and former President of Constellation, will not stand for re-election to the Board of Directors. His current term will conclude following Constellation's annual meeting of shareholders on May 15, 2026....

Dublin, March 27, 2026 (GLOBE NEWSWIRE) -- Fusion Fuel Green PLC (Nasdaq: HTOO) (“Fusion Fuel” or the “Company”), a leading provider of full-service energy engineering, advisory, and utility solutions, today highlighted information about its anticipated 2.0% Net Smelter Return (the “NSR”) royalty on two mineral claims – MC00040006 and MC0004007 – within a larger set of mineral claims held by the Shea Creek Joint Venture. The NSR is part of a portfolio of royalty rights that the Company anticipates will be acquired upon the closing of its previously announced agreement with Royal Uranium Inc. (“Royal Uranium”)....