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06.06.25 - 02:15
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HKEX: ADT of HK Securities Mkt Leaps 1.2x YoY in 5M25 (AAStocks)
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HKEX (00388.HK) latest disclosed data showed that the average daily turnover (ADT) of the Hong Kong securities market in the first five months of 2025 was HKD242.3 billion, up 120% YoY. The ADT in May was HKD210.3 billion, up 50% YoY.As of the end of May 2025, the total market cap of the Hong Kong securities market reached HKD40......
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27.05.25 - 14:06
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ASCO 2025: Phase III ARANOTE Post-hoc Analyses Presented on Health-Related Quality of Life and Pain Outcomes in Patients with Metastatic Castration-Sensitive Prostate Cancer Receiving NUBEQA® (darolutamide) plus ADT (Business Wire)
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NUBEQA® (darolutamide) is the first and only androgen receptor inhibitor (ARi) to show clinically meaningful delays in deterioration of important patient-relevant health-related quality of life (HRQoL) outcomes for patients with metastatic castration-sensitive prostate cancer (mCSPC)
In post-hoc analyses of the Phase III ARANOTE trial, patients treated with NUBEQA plus androgen deprivation therapy (ADT) had an extended time to deterioration in HRQoL, with an additional 5.1 months compared to placebo plus ADT (16.6 months versus 11.5 months; HR 0.76, 95% CI 0.61–0.93)
The results will be presented at the 2025 American Society of Clinical Oncology (ASCO) Annual Meeting
WHIPPANY, N.J.--(BUSINESS WIRE)--New post-hoc analyses from the investigational Phase III ARANOTE trial showed a clinically meaningful improvement in health-related quality of life (HRQoL) and delayed pain progression for metastatic castration-sensitive prostate cancer (mCSPC) patients treated with NUBEQA® (darolutamide) plus androgen dep...
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21.05.25 - 14:06
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Bayer Highlights New Data from Oncology and Women′s Health Portfolios at 2025 ASCO Annual Meeting (Business Wire)
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Post hoc analyses from the pivotal Phase III ARANOTE trial evaluating health-related quality of life (HRQoL) outcomes with NUBEQA® (darolutamide) plus androgen deprivation therapy (ADT) will be presented
Additional data include an analysis of the investigational Phase III PEACE III study of the first and only approved targeted alpha emitting radiopharmaceutical, XOFIGO® (radium-223 dichloride), that treats bone metastases in metastatic castration-resistant prostate cancer (mCRPC)
Safety and efficacy results for the investigational compound sevabertinib (BAY 2927088) in patients with advanced HER2-mutant non-small cell lung cancer (NSCLC) will also be showcased
Bayer will also present data from the Phase III OASIS-4 trial conducted outside of the U.S. of the investigational compound elinzanetant for the treatment of moderate to severe vasomotor symptoms (VMS, also known as hot flashes) caused by adjuvant endocrine therapy
Abstracts: 5004 | TPS5131 | 5048 | 5062 | 5007 | 8504 | 508 | 12063 |
WHIPPANY, N.J...
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30.04.25 - 10:45
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Research: JPM: HKEX 1Q25 Results Robust; Rating Kept Neutral (AAStocks)
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JP Morgan issued a research report covering HKEX (00388.HK), which delivered strong set of 1Q25 results, given remarkable growth in ADT for securities and derivatives, paired with increased NII. However, looking ahead, JP Morgan expected ADT to normalize. The broker maintained a Neutral rating on HKEX, noting that sustained chan......
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29.04.25 - 08:06
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Update on CAPItello-280 Phase III trial (Cision)
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29 April 2025
Update on CAPItello-280 Phase III trial of Truqap in metastatic castration-resistant prostate cancer
AstraZeneca is discontinuing the CAPItello-280 Phase III trial evaluating the efficacy and safety of Truqap (capivasertib) in combination with docetaxel and androgen-deprivation therapy (ADT) compared to docetaxel and ADT with placebo in patients with metastatic castration-resistant prostate cancer (mCRPC).
This decision is based on the recommendation of the Independent Data Monitoring Committee (IDMC) following their review of data from a pre-specified...
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